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The Yellow Medicine River is a tributary of the Minnesota River, 107 miles (173 km) long, in southwestern Minnesota in the United States. Via the Minnesota River, it is part of the watershed of the Mississippi River, draining an area of 665 square miles (1,722 km²) in an agricultural region. Its name is a translation of the Dakota name for the river, pajutazee, ("huta" meaning "root," "zi" meaning "yellow," and "kapi" meaning "they dig"),[citation needed] for the yellow root of the moonseed plant, which grows in vines along the river.[2]